Sandbox Reserved 1654: Difference between revisions

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CPEB proteins play a key role in some diseases, especially in cancers. Indeed, in some humans tumors the level of CPEB 1 is lower than in healthy cells and this leads to the growth of these tumors. An overexpression of CPEB 4 can lead to tumor growth too. Some researches try to find a cancer treatment thanks to CPEB mutations<ref name="publi" />.

Other diseases, like [https://en.wikipedia.org/wiki/Fragile_X_syndrome Fragile X syndrome], could be treated by regulating the expression of CPEB. Indeed, this disease is due to a mutation on [https://en.wikipedia.org/wiki/FMR1 FRM1 gene], which is bind to X chromosome. Because of this mutation, FMRP, which is a translational repressor protein, isn’t expressed. So, proteins are overexpressed and it could be the cause of some dysfunctions observed for this disease. That’s why the regulation of the level of CPEB could treat this syndrome.

Other diseases, like [https://en.wikipedia.org/wiki/Fragile_X_syndrome Fragile X syndrome], could be treated by regulating the expression of CPEB. Indeed, this disease is due to a mutation on [https://en.wikipedia.org/wiki/FMR1 FRM1 gene], which is bind to X chromosome. Because of this mutation, FMRP, which is a translational repressor protein, isn’t expressed. So, proteins are overexpressed and it could be the cause of some dysfunctions observed for this disease. That’s why the regulation of the level of CPEB could treat this syndrome<ref>doi: 10.1038/nm.3353</ref>.

== References ==

Sandbox Reserved 1654: Difference between revisions

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@@ Line 41: / Line 41: @@
 CPEB proteins play a key role in some diseases, especially in cancers. Indeed, in some humans tumors the level of CPEB 1 is lower than in healthy cells and this leads to the growth of these tumors. An overexpression of CPEB 4 can lead to tumor growth too. Some researches try to find a cancer treatment thanks to CPEB mutations<ref name="publi" />.
-Other diseases, like [https://en.wikipedia.org/wiki/Fragile_X_syndrome Fragile X syndrome], could be treated by regulating the expression of CPEB. Indeed, this disease is due to a mutation on [https://en.wikipedia.org/wiki/FMR1 FRM1 gene], which is bind to X chromosome. Because of this mutation, FMRP, which is a translational repressor protein, isn’t expressed. So, proteins are overexpressed and it could be the cause of some dysfunctions observed for this disease.  That’s why the regulation of the level of CPEB could treat this syndrome.
+Other diseases, like [https://en.wikipedia.org/wiki/Fragile_X_syndrome Fragile X syndrome], could be treated by regulating the expression of CPEB. Indeed, this disease is due to a mutation on [https://en.wikipedia.org/wiki/FMR1 FRM1 gene], which is bind to X chromosome. Because of this mutation, FMRP, which is a translational repressor protein, isn’t expressed. So, proteins are overexpressed and it could be the cause of some dysfunctions observed for this disease.  That’s why the regulation of the level of CPEB could treat this syndrome<ref>doi: 10.1038/nm.3353</ref>.
 == References ==
 <references/>