Sandbox Reserved 1650: Difference between revisions
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The complex and particularly stable structure of TG gives it iodide reservoir properties. Indeed, all iodinated but non-hormonoid tyrosines are useful for iodine storage in the thyroid gland. | The complex and particularly stable structure of TG gives it iodide reservoir properties. Indeed, all iodinated but non-hormonoid tyrosines are useful for iodine storage in the thyroid gland. | ||
== Interest in the medical field == | == Interest in the medical field<ref>DOI 17614775</ref><ref>DOI 12721190</ref><ref>DOI 24147207</ref><ref>DOI 11788684</ref><ref>DOI 17201802</ref><ref>DOI 10.1677/ERC-10-0292</ref><ref>DOI 5773064</ref><ref>DOI 3681445</ref><ref>DOI 12089177</ref><ref>DOI 21134539</ref><ref>DOI 6814409</ref><ref>DOI 29984794</ref><ref>DOI 21649472</ref><ref>DOI 28593684</ref><ref>DOI 29246752</ref><ref>DOI : 10.1001/jama.1979.03290350043022</ref> == | ||
=== Modification of the TG quantity related to the desease === | === Modification of the TG quantity related to the desease === | ||
A healthy subject has between 5 and 25 µg of TG per liter of blood. In case of thyroid dysfunction, this level may increase or decrease. For example, it decreases in the case of congenital athyreosis (insufficiency of the thyroid gland) or prior to a miscarriage due to the presence of anti-TG antibodies, but increases in the case of cancer, thyroiditis, inflammation of the thyroid or autoimmune thyroid diseases AITD (Grave's disease, Hashimoto's thyroiditis). | A healthy subject has between 5 and 25 µg of TG per liter of blood. In case of thyroid dysfunction, this level may increase or decrease. For example, it decreases in the case of congenital athyreosis (insufficiency of the thyroid gland) or prior to a miscarriage due to the presence of anti-TG antibodies, but increases in the case of cancer, thyroiditis, inflammation of the thyroid or autoimmune thyroid diseases AITD (Grave's disease, Hashimoto's thyroiditis). | ||