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==5CZX==

The neurogenic locus notch homolog protein 3 is a protein encoded by the NOTCH3 gene. There are 4 notch receptors in mammals, all of which are transmembrane proteins and notch signalling regulates a very diverse set of biological functions; The most commun is the cell lineage determination. Therefore, changes in the activity of these receptors is associated with various benign and malignant diseases as T-ALL (T-lineage acute lymphoblastic leukemia). T-ALL is characterized by the uncontrolled proliferation of T-cell lymphoblasts in the blood, the brown marrow and the tissues.

The neurogenic locus notch homolog protein 3 is a protein encoded by the [https://en.wikipedia.org/wiki/Notch_3 NOTCH3 gene]. There are 4 notch receptors in mammals, all of which are transmembrane proteins and notch signalling regulates a very diverse set of biological functions; The most commun is the cell lineage determination. Therefore, changes in the activity of these receptors is associated with various benign and malignant diseases as T-ALL (T-lineage acute lymphoblastic leukemia). T-ALL is characterized by the uncontrolled proliferation of T-cell lymphoblasts in the blood, the brown marrow and the tissues.

== Function ==

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 ==5CZX==
 <StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=''>
-The neurogenic locus notch homolog protein 3 is a protein encoded by the NOTCH3 gene. There are 4 notch receptors in mammals, all of which are transmembrane proteins and notch signalling regulates a very diverse set of biological functions; The most commun is the cell lineage determination. Therefore, changes in the activity of these receptors is associated with various benign and malignant diseases as T-ALL (T-lineage acute lymphoblastic leukemia). T-ALL is characterized by the uncontrolled proliferation of T-cell lymphoblasts in the blood, the brown marrow and the tissues.
+The neurogenic locus notch homolog protein 3 is a protein encoded by the [https://en.wikipedia.org/wiki/Notch_3 NOTCH3 gene]. There are 4 notch receptors in mammals, all of which are transmembrane proteins and notch signalling regulates a very diverse set of biological functions; The most commun is the cell lineage determination. Therefore, changes in the activity of these receptors is associated with various benign and malignant diseases as T-ALL (T-lineage acute lymphoblastic leukemia). T-ALL is characterized by the uncontrolled proliferation of T-cell lymphoblasts in the blood, the brown marrow and the tissues.
 == Function ==