Sandbox Reserved 1649: Difference between revisions
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== Regulation == | == Regulation == | ||
A high quantity of stress can lead to the overactivation of NMDA receptors. Therefore, a regulation can occur on NMDA receptors in order to avoid any neuronal injury. This very important regulation can act at the level of NR2A subunit. | A high quantity of stress can lead to the overactivation of NMDA receptors. Therefore, a regulation can occur on NMDA receptors in order to avoid any neuronal injury. <ref name="Structural Rearrangements of NR1/NR2A NMDA Receptors during Allosteric Inhibition">DOI 10.1016/j.neuron.2010.08.011</ref> This very important regulation can act at the level of NR2A subunit. | ||
For now, scientists know that regulation can occur in several ways: either a modification directly affects the functioning of the receptor, or the quantity of receptors at the surface of the neuron by modifying NR2A itself or not. | For now, scientists know that regulation can occur in several ways: either a modification directly affects the functioning of the receptor, or the quantity of receptors at the surface of the neuron by modifying NR2A itself or not. | ||
