Sandbox Reserved 1646: Difference between revisions
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'''<scene name='86/868179/N-terminus/2'>N terminus</scene>:''' fits in cavity (contact to surrounding residues: N102, Q174, and F178 from TM2 and TM4) indicating a distinct roles in mediating binding of different ligands. However, it is not engaged in GnRH activation of wild-type GnRH1R. | '''<scene name='86/868179/N-terminus/2'>N terminus</scene>:''' fits in cavity (contact to surrounding residues: N102, Q174, and F178 from TM2 and TM4) indicating a distinct roles in mediating binding of different ligands. However, it is not engaged in GnRH activation of wild-type GnRH1R. | ||
'''Y283:''' engaged in the ligand recognition and activation of GnRH1R29 together with | '''<scene name='86/868179/Binding_pocket_bottem/1'>Y283:</scene>''' engaged in the ligand recognition and activation of GnRH1R29 together with Y284 and M125 are suggested to form the bottom wall | ||
=== Signal transduction === | === Signal transduction === | ||
