Sandbox Reserved 1648: Difference between revisions
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=='''3V6O: Leptin receptor-antibody complex'''== | =='''3V6O: Leptin receptor-antibody complex'''== | ||
<StructureSection load='3v6o' size='340' side='right' frame='true' caption='Leptin receptor' scene=''> | <StructureSection load='3v6o' size='340' side='right' frame='true' caption='Leptin receptor' scene=''> | ||
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In the '''FN III''' domains, there are two conserved '''cysteines''' ('''Cys-672 and Cys-751''' <ref>Leptin receptor activation depends on critical cysteine residues in its fibronectin type III subdomains : https://www.jbc.org/article/S0021-9258(20)61429-6/fulltext </ref>) that are crucial for the activation of the receptor. | In the '''FN III''' domains, there are two conserved '''cysteines''' ('''Cys-672 and Cys-751''' <ref>Leptin receptor activation depends on critical cysteine residues in its fibronectin type III subdomains : https://www.jbc.org/article/S0021-9258(20)61429-6/fulltext </ref>) that are crucial for the activation of the receptor. | ||
Moreover, in order to form an | Moreover, in order to form an <scene name='86/868181/Activated_leptin_obr_complex/1'>'''activated 2:4 leptin:ObR complex'''</scene>., the leptin clusters '''two pre-formed ObR dimers'''. | ||
== '''Signaling pathways''' == | == '''Signaling pathways''' == | ||
