2cyx: Difference between revisions

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<StructureSection load='2cyx' size='340' side='right'caption='[[2cyx]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
<StructureSection load='2cyx' size='340' side='right'caption='[[2cyx]], [[Resolution|resolution]] 2.56&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2cyx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYX FirstGlance]. <br>
<table><tr><td colspan='2'>[[2cyx]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CYX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CYX FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBE2G2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cyx OCA], [https://pdbe.org/2cyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cyx RCSB], [https://www.ebi.ac.uk/pdbsum/2cyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cyx ProSAT], [https://www.topsan.org/Proteins/RSGI/2cyx TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cyx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cyx OCA], [https://pdbe.org/2cyx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cyx RCSB], [https://www.ebi.ac.uk/pdbsum/2cyx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cyx ProSAT], [https://www.topsan.org/Proteins/RSGI/2cyx TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UB2G2_HUMAN UB2G2_HUMAN]] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).<ref>PMID:20061386</ref> <ref>PMID:22607976</ref>
[https://www.uniprot.org/uniprot/UB2G2_HUMAN UB2G2_HUMAN] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).<ref>PMID:20061386</ref> <ref>PMID:22607976</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Ubiquitin conjugating enzyme|Ubiquitin conjugating enzyme]]
*[[3D structures of ubiquitin conjugating enzyme|3D structures of ubiquitin conjugating enzyme]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ubiquitin--protein ligase]]
[[Category: Arai R]]
[[Category: Arai, R]]
[[Category: Imai Y]]
[[Category: Imai, Y]]
[[Category: Murayama K]]
[[Category: Murayama, K]]
[[Category: Shirouzu M]]
[[Category: Structural genomic]]
[[Category: Takahashi R]]
[[Category: Shirouzu, M]]
[[Category: Yokoyama S]]
[[Category: Takahashi, R]]
[[Category: Yoshikawa S]]
[[Category: Yokoyama, S]]
[[Category: Yoshikawa, S]]
[[Category: Ligase]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Rsgi]]
[[Category: Ubl conjugation pathway]]
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