1dpr: Difference between revisions

Line 1:

[[Image:1dpr.~~jpg~~|left|200px]]

[[Image:1dpr.png|left|200px]]

<!--

Line 9:

Line 10:

~~'''~~STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE~~'''~~

===STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE===

~~==Overview==~~

<!--

The ~~diphtheria tox repressor (DtxR) of Corynebacterium diphtheriae plays a critical role in~~ the ~~regulation of diphtheria toxin expression and~~ the ~~control of other iron-sensitive genes~~. ~~The crystal structures of apo-DtxR and of the metal ion-activated form of the repressor have been solved and used to identify motifs involved in DNA and metal ion binding~~. ~~Residues involved in binding of the activated repressor to~~ the ~~diphtheria tox operator, glutamine 43, arginine 47, and arginine 50, were located and confirmed by site-directed mutagenesis~~. ~~Previous biochemical and genetic data can be explained in terms of these structures. Conformational differences between apo~~- ~~and Ni~~-~~DtxR are discussed with regard to the mechanism of action of this repressor.~~

The line below this paragraph, {{ABSTRACT_PUBMED_7568230}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 7568230 is the PubMed ID number.

-->

==About this Structure==

Line 31:

Line 35:

[[Category: Iron-regulation repressor]]

[[Category: Virulence]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May 2 14~~:07~~:40~~ 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:26:07 2008''

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-[[Image:1dpr.jpg|left|200px]]
+{{Seed}}
+[[Image:1dpr.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1dpr|  PDB=1dpr  |  SCENE=  }}
-'''STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE'''
+===STRUCTURES OF THE APO-AND METAL ION ACTIVATED FORMS OF THE DIPHTHERIA TOX REPRESSOR FROM CORYNEBACTERIUM DIPHTHERIAE===
-==Overview==
+<!--
-The diphtheria tox repressor (DtxR) of Corynebacterium diphtheriae plays a critical role in the regulation of diphtheria toxin expression and the control of other iron-sensitive genes. The crystal structures of apo-DtxR and of the metal ion-activated form of the repressor have been solved and used to identify motifs involved in DNA and metal ion binding. Residues involved in binding of the activated repressor to the diphtheria tox operator, glutamine 43, arginine 47, and arginine 50, were located and confirmed by site-directed mutagenesis. Previous biochemical and genetic data can be explained in terms of these structures. Conformational differences between apo- and Ni-DtxR are discussed with regard to the mechanism of action of this repressor.
+The line below this paragraph, {{ABSTRACT_PUBMED_7568230}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 7568230 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_7568230}}
 ==About this Structure==
@@ Line 31: / Line 35: @@
 [[Category: Iron-regulation repressor]]
 [[Category: Virulence]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 14:07:40 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:26:07 2008''