6kog: Difference between revisions
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<StructureSection load='6kog' size='340' side='right'caption='[[6kog]], [[Resolution|resolution]] 1.68Å' scene=''> | <StructureSection load='6kog' size='340' side='right'caption='[[6kog]], [[Resolution|resolution]] 1.68Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6kog]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[6kog]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyricularia_oryzae_70-15 Pyricularia oryzae 70-15]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KOG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KOG FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.68Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kog OCA], [https://pdbe.org/6kog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kog RCSB], [https://www.ebi.ac.uk/pdbsum/6kog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kog ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kog FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kog OCA], [https://pdbe.org/6kog PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kog RCSB], [https://www.ebi.ac.uk/pdbsum/6kog PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kog ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/TAS1_MAGO7 TAS1_MAGO7] Hybrid PKS-NRPS synthetase that mediates the biosynthesis of the toxin tenuazonic acid (TeA), an inhibitor of protein biosynthesis on ribosomes by suppressing the release of new protein (PubMed:26503170). TAS1 alone is sufficient for TeA synthesis (PubMed:26503170). The NRPS part performs the condensation of isoleucine with acetoacetyl-CoA and the final cyclization step is conducted by the KS domain (PubMed:26503170).<ref>PMID:26503170</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Pyricularia oryzae 70-15]] | ||
[[Category: Hino | [[Category: Hino T]] | ||
[[Category: Motoyama | [[Category: Motoyama T]] | ||
[[Category: Nagano | [[Category: Nagano S]] | ||
[[Category: Nishimoto | [[Category: Nishimoto K]] | ||
[[Category: Osada | [[Category: Osada H]] | ||
[[Category: Yun | [[Category: Yun CS]] | ||
