Sandbox Reserved 1661: Difference between revisions
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Anaïs Kembou (talk | contribs) No edit summary |
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Until 1985, injections of GH were carried out for people suffering from dwarfism. As it could only be obtained by extraction from the pituitary glands of dead people, it could only be extracted in small quantities, so resources were limited. Also this therapeutic treatment has been stopped in many countries, due to the possible contamination of the hormone by [https://en.wikipedia.org/wiki/Prion prions], which can cause serious diseases such as [https://en.wikipedia.org/wiki/Creutzfeldt%E2%80%93Jakob_disease Creutzfeldt-Jakob disease].<ref name="bgh" /> As a result, biosynthetic synthesis of the hormone is carried out by developing [https://en.wikipedia.org/wiki/List_of_recombinant_proteins recombinant proteins] of GH or IGF-1.<ref name="univ"/> | Until 1985, injections of GH were carried out for people suffering from dwarfism. As it could only be obtained by extraction from the pituitary glands of dead people, it could only be extracted in small quantities, so resources were limited. Also this therapeutic treatment has been stopped in many countries, due to the possible contamination of the hormone by [https://en.wikipedia.org/wiki/Prion prions], which can cause serious diseases such as [https://en.wikipedia.org/wiki/Creutzfeldt%E2%80%93Jakob_disease Creutzfeldt-Jakob disease].<ref name="bgh" /> As a result, biosynthetic synthesis of the hormone is carried out by developing [https://en.wikipedia.org/wiki/List_of_recombinant_proteins recombinant proteins] of GH or IGF-1.<ref name="univ"/> | ||
Affected by gigantism pathology, individuals may have therapeutic radiation and therapeutic drug treatment or synthesis of inhibitors such as [https://en.wikipedia.org/wiki/Somatostatin somatostatin], which act as GH antagonists by binding to the receptor, thus preventing the GH to perform its functions<ref name="bgh"/> | Affected by gigantism pathology, individuals may have therapeutic radiation and therapeutic drug treatment or synthesis of inhibitors such as [https://en.wikipedia.org/wiki/Somatostatin somatostatin], which act as GH antagonists by binding to the receptor, thus preventing the GH to perform its functions.<ref name="bgh"/> | ||
== References == | == References == | ||
<references/> | <references/> | ||
