AlphaFold2 examples from CASP 14: Difference between revisions
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===ORF8 Sidechain Accuracy=== | ===ORF8 Sidechain Accuracy=== | ||
Table I gives RMSD values for all atoms, which is one indication of sidechain accuracy. Another is prediction of [[salt bridges]] and [[cation-pi interactions]]. As detailed in Tables II and III: | Table I gives RMSD values for all atoms, which is one indication of sidechain accuracy. Another is prediction of [[salt bridges]] and [[cation-pi interactions]]. As detailed in Tables II and III: | ||
*AlphaFold2's prediction was '''correct for one of two''' salt bridges, and predicted '''no incorrect''' salt bridges. | *AlphaFold2's prediction was correct for 4/5 interactions, with one incorrect interaction. | ||
*AlphaFold2's prediction was '''correct for three of three''' cation-pi interactions, but predicted '''one incorrect''' interaction. | **AlphaFold2's prediction was '''correct for one of two''' salt bridges, and predicted '''no incorrect''' salt bridges. | ||
*The 2nd best prediction was '''correct for one of two''' salt bridges, but predicted '''two incorrect''' salt bridges. | **AlphaFold2's prediction was '''correct for three of three''' cation-pi interactions, but predicted '''one incorrect''' interaction. | ||
*The 2nd best prediction '''failed to predict any''' of the three cation-pi interactions, predicting zero interactions. | *The 2nd best prediction was correct for 1/5 interactions, with 2 incorrect interactions. | ||
**The 2nd best prediction was '''correct for one of two''' salt bridges, but predicted '''two incorrect''' salt bridges. | |||
**The 2nd best prediction '''failed to predict any''' of the three cation-pi interactions, predicting zero interactions. | |||
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