7bl1: Difference between revisions
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==== | ==human complex II-BATS bound to membrane-attached Rab5a-GTP== | ||
<StructureSection load='7bl1' size='340' side='right'caption='[[7bl1]]' scene=''> | <StructureSection load='7bl1' size='340' side='right'caption='[[7bl1]], [[Resolution|resolution]] 9.80Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7bl1]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BL1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BL1 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bl1 OCA], [https://pdbe.org/7bl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bl1 RCSB], [https://www.ebi.ac.uk/pdbsum/7bl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bl1 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 9.8Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bl1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bl1 OCA], [https://pdbe.org/7bl1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bl1 RCSB], [https://www.ebi.ac.uk/pdbsum/7bl1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bl1 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PI3R4_HUMAN PI3R4_HUMAN] Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate; different complex forms are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123).<ref>PMID:20643123</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Bertram J]] | ||
[[Category: Briggs JAG]] | |||
[[Category: Kovtun O]] | |||
[[Category: Morado DR]] | |||
[[Category: Munro S]] | |||
[[Category: Ohashi Y]] | |||
[[Category: Perisic O]] | |||
[[Category: Tremel S]] | |||
[[Category: Williams RL]] | |||
Latest revision as of 07:48, 1 May 2024
human complex II-BATS bound to membrane-attached Rab5a-GTP
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