7ajr: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7ajr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AJR FirstGlance]. <br> | <table><tr><td colspan='2'>[[7ajr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AJR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AJR FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RJB:2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-1,3-dihydroinden-2-yl]ethanoic+acid'>RJB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=RJB:2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-1,3-dihydroinden-2-yl]ethanoic+acid'>RJB</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ajr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ajr OCA], [https://pdbe.org/7ajr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ajr RCSB], [https://www.ebi.ac.uk/pdbsum/7ajr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ajr ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ajr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ajr OCA], [https://pdbe.org/7ajr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ajr RCSB], [https://www.ebi.ac.uk/pdbsum/7ajr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ajr ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/E3ULB4_PSEAI E3ULB4_PSEAI] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Behria | [[Category: Behria L]] | ||
[[Category: Bodnarchuk | [[Category: Bodnarchuk MS]] | ||
[[Category: Castandet | [[Category: Castandet J]] | ||
[[Category: Davies | [[Category: Davies DT]] | ||
[[Category: Everett | [[Category: Everett M]] | ||
[[Category: Forrest | [[Category: Forrest AK]] | ||
[[Category: Jones | [[Category: Jones MW]] | ||
[[Category: Karunakar | [[Category: Karunakar P]] | ||
[[Category: Kotha | [[Category: Kotha V]] | ||
[[Category: Leiris | [[Category: Leiris S]] | ||
[[Category: Lemonnier | [[Category: Lemonnier M]] | ||
[[Category: Martha | [[Category: Martha SK]] | ||
[[Category: Mullins | [[Category: Mullins TMG]] | ||
[[Category: Pallin | [[Category: Pallin TD]] | ||
[[Category: Parusharamulu | [[Category: Parusharamulu B]] | ||
[[Category: Pothukanuri | [[Category: Pothukanuri S]] | ||
[[Category: Pottabathini | [[Category: Pottabathini N]] | ||
[[Category: Ramula | [[Category: Ramula R]] | ||
[[Category: Sprinsky | [[Category: Sprinsky N]] | ||
[[Category: Sutton | [[Category: Sutton JM]] | ||
Revision as of 12:10, 1 February 2024
Virtual screening approach leading to the identification of a novel and tractable series of Pseudomonas aeruginosa elastase inhibitors
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