AlphaFold2 examples from CASP 14: Difference between revisions
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==Phage RNA polymerase T1037== | ==Phage RNA polymerase T1037== | ||
Our second example is a 404-residue domain within a 2,180 residue RNA polymerase, [[6vr4]], gp66 from a bacteriophage of the crAss-like group, some members of which are prevalent in the human gut<ref name="6vr4" />. One known host for the target-containing phage is gram-negative, aerobic bacteria ''Cellulphaga baltica'' isolated from marine microalgae<ref name="6vr4" /><ref name="cb">PMID: 10425785</ref>. This RNA polymerase is packaged in the virion, and delivered into the host cell, where it transcribes early phage genes<ref name="6vr4" />. CASP 14 classified this domain, coded '''T1037''', as a free modeling ("FM") target, meaning that no informative templates existed in the [[PDB]]. | Our second example is a 404-residue domain within a 2,180 residue RNA polymerase, [[6vr4]], gp66 from a bacteriophage of the crAss-like group, some members of which are prevalent in the human gut<ref name="6vr4" />. One known host for the target-containing phage is gram-negative, aerobic bacteria ''Cellulphaga baltica'' isolated from marine microalgae<ref name="6vr4" /><ref name="cb">PMID: 10425785</ref>. This RNA polymerase is packaged in the virion, and delivered into the host cell, where it transcribes early phage genes<ref name="6vr4" />. CASP 14 classified this domain, coded '''T1037''', as a free modeling ("FM") target<ref name="casp14domains" />, meaning that no informative templates existed in the [[PDB]]. | ||
===X-ray crystal structure=== | ===X-ray crystal structure=== | ||
