1dvi: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:1dvi.gif|left|200px]]
{{Seed}}
[[Image:1dvi.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1dvi|  PDB=1dvi  |  SCENE=  }}  
{{STRUCTURE_1dvi|  PDB=1dvi  |  SCENE=  }}  


'''CALPAIN DOMAIN VI WITH CALCIUM BOUND'''
===CALPAIN DOMAIN VI WITH CALCIUM BOUND===




==Overview==
<!--  
The crystal structure of a Ca(2+)-binding domain (dVI) of rat m-calpain has been determined at 2.3 A resolution, both with and without bound Ca2+. The structures reveal a unique fold incorporating five EF-hand motifs per monomer, three of which bind calcium at physiological calcium concentrations, with one showing a novel EF-hand coordination pattern. This investigation gives us a first view of the calcium-induced conformational changes, and consequently an insight into the mechanism of calcium induced activation in calpain. The crystal structures reveal a dVI homodimer which provides a preliminary model for the subunit dimerization in calpain.
The line below this paragraph, {{ABSTRACT_PUBMED_9228945}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 9228945 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_9228945}}


==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Calcium-dependent protease]]
[[Category: Calcium-dependent protease]]
[[Category: Small subunit]]
[[Category: Small subunit]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 14:19:48 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:40:56 2008''

Revision as of 20:40, 30 June 2008

File:1dvi.png

Template:STRUCTURE 1dvi

CALPAIN DOMAIN VI WITH CALCIUM BOUND

Template:ABSTRACT PUBMED 9228945

About this Structure

1DVI is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

Structure of a calpain Ca(2+)-binding domain reveals a novel EF-hand and Ca(2+)-induced conformational changes., Blanchard H, Grochulski P, Li Y, Arthur JS, Davies PL, Elce JS, Cygler M, Nat Struct Biol. 1997 Jul;4(7):532-8. PMID:9228945

Page seeded by OCA on Mon Jun 30 23:40:56 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA