1f0l: Difference between revisions
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== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/DTX_CORBE DTX_CORBE] Diphtheria toxin, produced by a phage infecting Corynebacterium diphtheriae, is a proenzyme that, after activation, catalyzes the covalent attachment of the ADP ribose moiety of NAD to eukaryotic elongation factor 2 (eEF-2). Fragment A is the catalytic portion responsible for enzymatic ADP-ribosylation of elongation factor 2, while fragment B is responsible for binding of toxin to cell receptors and entry of fragment A.<ref>PMID:18276581</ref> <ref>PMID:19793133</ref> | |||
==See Also== | ==See Also== | ||
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[[Category: Corynebacterium diphtheriae]] | [[Category: Corynebacterium diphtheriae]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Eisenberg | [[Category: Eisenberg D]] | ||
[[Category: Steere | [[Category: Steere B]] | ||
