7cz6: Difference between revisions

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<StructureSection load='7cz6' size='340' side='right'caption='[[7cz6]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
<StructureSection load='7cz6' size='340' side='right'caption='[[7cz6]], [[Resolution|resolution]] 4.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7cz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Omono_river_virus Omono river virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CZ6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[7cz6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Omono_River_virus Omono River virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7CZ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7CZ6 FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cz6 OCA], [https://pdbe.org/7cz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cz6 RCSB], [https://www.ebi.ac.uk/pdbsum/7cz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cz6 ProSAT]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.1&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7cz6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7cz6 OCA], [https://pdbe.org/7cz6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7cz6 RCSB], [https://www.ebi.ac.uk/pdbsum/7cz6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7cz6 ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Function ==
== Publication Abstract from PubMed ==
[https://www.uniprot.org/uniprot/A0A7M3VBX7_9VIRU A0A7M3VBX7_9VIRU]
Mosquito viruses cause unpredictable outbreaks of disease. Recently, several unassigned viruses isolated from mosquitoes, including the Omono River virus (OmRV), were identified as totivirus-like viruses, with features similar to those of the Totiviridae family. Most reported members of this family infect fungi or protozoans and lack an extracellular life cycle stage. Here, we identified a new strain of OmRV and determined high-resolution structures for this virus using single-particle cryo-electron microscopy. The structures feature an unexpected protrusion at the five-fold vertex of the capsid. Disassociation of the protrusion could result in several conformational changes in the major capsid. All these structures, together with some biological results, suggest the protrusions' associations with the extracellular transmission of OmRV.
 
Cryo-EM reveals a previously unrecognized structural protein of a dsRNA virus implicated in its extracellular transmission.,Shao Q, Jia X, Gao Y, Liu Z, Zhang H, Tan Q, Zhang X, Zhou H, Li Y, Wu, Zhang Q PLoS Pathog. 2021 Mar 17;17(3):e1009396. doi: 10.1371/journal.ppat.1009396., eCollection 2021 Mar. PMID:33730056<ref>PMID:33730056</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 7cz6" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Omono river virus]]
[[Category: Omono River virus]]
[[Category: Gao, Y]]
[[Category: Gao Y]]
[[Category: Jia, X]]
[[Category: Jia X]]
[[Category: Liu, Z]]
[[Category: Liu Z]]
[[Category: Shao, Q]]
[[Category: Shao Q]]
[[Category: Five-fold vertex]]
[[Category: Pentamer]]
[[Category: Protrusion]]
[[Category: Viral protein]]

Latest revision as of 10:52, 27 March 2024

Protrusion structure of Omono River virus

7cz6, resolution 4.10Å

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