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==TRANSLATION INITIATION FACTOR IF3 FROM ESCHERICHIA COLI RIBOSOME BINDING DOMAIN (RESIDUES 84-180)==
==TRANSLATION INITIATION FACTOR IF3 FROM ESCHERICHIA COLI RIBOSOME BINDING DOMAIN (RESIDUES 84-180)==
<StructureSection load='2ife' size='340' side='right'caption='[[2ife]], [[NMR_Ensembles_of_Models | 24 NMR models]]' scene=''>
<StructureSection load='2ife' size='340' side='right'caption='[[2ife]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ife]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ife 1ife]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IFE FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ife]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1ife 1ife]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IFE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IFE FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">INFC CODONS 84-180 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ife FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ife OCA], [https://pdbe.org/2ife PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ife RCSB], [https://www.ebi.ac.uk/pdbsum/2ife PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ife ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ife FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ife OCA], [https://pdbe.org/2ife PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ife RCSB], [https://www.ebi.ac.uk/pdbsum/2ife PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ife ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/IF3_ECOLI IF3_ECOLI]] IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.[HAMAP-Rule:MF_00080]  
[https://www.uniprot.org/uniprot/IF3_ECOLI IF3_ECOLI] IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.[HAMAP-Rule:MF_00080]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Cock, E De]]
[[Category: Dardel F]]
[[Category: Dardel, F]]
[[Category: De Cock E]]
[[Category: Garcia, C]]
[[Category: Garcia C]]
[[Category: Gene regulation]]
[[Category: Initiation factor]]
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