2ihc: Difference between revisions

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<StructureSection load='2ihc' size='340' side='right'caption='[[2ihc]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
<StructureSection load='2ihc' size='340' side='right'caption='[[2ihc]], [[Resolution|resolution]] 2.44&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ihc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IHC FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ihc]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IHC FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BACH1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.44&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ihc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihc OCA], [https://pdbe.org/2ihc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ihc RCSB], [https://www.ebi.ac.uk/pdbsum/2ihc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ihc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ihc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ihc OCA], [https://pdbe.org/2ihc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ihc RCSB], [https://www.ebi.ac.uk/pdbsum/2ihc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ihc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/BACH1_HUMAN BACH1_HUMAN]] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.  
[https://www.uniprot.org/uniprot/BACH1_HUMAN BACH1_HUMAN] Transcriptional regulator that acts as repressor or activator. Binds, in vitro, to NF-E2 binding sites. Play important roles in coordinating transcription activation and repression by MAFK.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Amos, A L]]
[[Category: Amos AL]]
[[Category: Arrowsmith, C]]
[[Category: Arrowsmith C]]
[[Category: Bullock, A]]
[[Category: Bullock A]]
[[Category: Bunkoczi, G]]
[[Category: Bunkoczi G]]
[[Category: Delft, F von]]
[[Category: Edwards A]]
[[Category: Edwards, A]]
[[Category: Gorrec F]]
[[Category: Gorrec, F]]
[[Category: Knapp S]]
[[Category: Knapp, S]]
[[Category: Papagrigoriou E]]
[[Category: Papagrigoriou, E]]
[[Category: Sundstrom M]]
[[Category: Structural genomic]]
[[Category: Turnbull AP]]
[[Category: Sundstrom, M]]
[[Category: Umeano C]]
[[Category: Turnbull, A P]]
[[Category: Weigelt J]]
[[Category: Umeano, C]]
[[Category: Von Delft F]]
[[Category: Weigelt, J]]
[[Category: Bach1]]
[[Category: Bric-a-brac domain]]
[[Category: Cap'n'collar type of basic region leucine zipper factor family]]
[[Category: Protein-protein interaction]]
[[Category: Sgc]]
[[Category: Transcription]]
[[Category: Transcription factor]]

Latest revision as of 10:11, 30 August 2023

Crystal structure of the bric-a-brac (BTB) domain of human BACH1

2ihc, resolution 2.44Å

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