2ija: Difference between revisions
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<StructureSection load='2ija' size='340' side='right'caption='[[2ija]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='2ija' size='340' side='right'caption='[[2ija]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2ija]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2ija]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IJA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2IJA FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.701Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACM:ACETAMIDE'>ACM</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ija FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ija OCA], [https://pdbe.org/2ija PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ija RCSB], [https://www.ebi.ac.uk/pdbsum/2ija PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ija ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ija FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ija OCA], [https://pdbe.org/2ija PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ija RCSB], [https://www.ebi.ac.uk/pdbsum/2ija PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ija ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/ARY1_HUMAN ARY1_HUMAN] Participates in the detoxification of a plethora of hydrazine and arylamine drugs. Catalyzes the N- or O-acetylation of various arylamine and heterocyclic amine substrates and is able to bioactivate several known carcinogens. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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<jmolCheckbox> | <jmolCheckbox> | ||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ij/2ija_consurf.spt"</scriptWhenChecked> | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ij/2ija_consurf.spt"</scriptWhenChecked> | ||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
</jmolCheckbox> | </jmolCheckbox> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Arrowsmith | [[Category: Arrowsmith CH]] | ||
[[Category: Bochkarev | [[Category: Bochkarev A]] | ||
[[Category: Dombrovski | [[Category: Dombrovski L]] | ||
[[Category: Edwards | [[Category: Edwards AM]] | ||
[[Category: Grant | [[Category: Grant DM]] | ||
[[Category: Loppnau | [[Category: Loppnau P]] | ||
[[Category: Plotnikov | [[Category: Plotnikov AN]] | ||
[[Category: Sundstrom M]] | |||
[[Category: Sundstrom | [[Category: Tempel W]] | ||
[[Category: Tempel | [[Category: Weigelt J]] | ||
[[Category: Weigelt | [[Category: Wu H]] | ||
[[Category: Wu | |||
Latest revision as of 01:04, 21 November 2024
Human N-acetyltransferase 1 F125S mutant
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