CHD4 Sandbox: Difference between revisions
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The nucleosome is comprised of <scene name='88/880268/147-mer/2'>146-147 DNA base pairs</scene> wrapped around an <scene name='88/880268/147-mer_octamer/1'>octamer</scene> of four different proteins called histones. | The nucleosome is comprised of <scene name='88/880268/147-mer/2'>146-147 DNA base pairs</scene> wrapped around an <scene name='88/880268/147-mer_octamer/1'>octamer</scene> of four different proteins called histones. | ||
===The Histones=== | ===The Histones=== | ||
The four histone proteins: <scene name='88/880268/H4_in_complex/1'>H4</scene>, H3, H2A, and H2B make up the nucleosome with two sets of two heterodimers[2]. Heterodimers consisting of H3 and H4 as well as H2A and H2B[2]. These heterodimers form an octamer through the presence of hydrophobic interaction between dimers[2]. | The four histone proteins: <scene name='88/880268/H4_in_complex/1'>H4</scene>, <scene name='88/880268/H3_histone/1'> H3</scene>, H2A, and H2B make up the nucleosome with two sets of two heterodimers[2]. Heterodimers consisting of H3 and H4 as well as H2A and H2B[2]. These heterodimers form an octamer through the presence of hydrophobic interaction between dimers[2]. | ||
==The Dyad Axis== | ==The Dyad Axis== | ||
The formation of the histones via hydrophobic interactions forms the octamer[2]. This octamer has dyad symmetry between the H3 and H3 histones, forming the dyad axis and referred to as super helical location 0 (SHL 0) [2]. | The formation of the histones via hydrophobic interactions forms the octamer[2]. This octamer has dyad symmetry between the H3 and H3 histones, forming the dyad axis and referred to as super helical location 0 (SHL 0) [2]. | ||
