Receptor: Difference between revisions
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*[[Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptors in general]] | *[[Nicotinic Acetylcholine Receptor|Nicotinic Acetylcholine Receptors in general]] | ||
The receptor is a transmembrane pentameric glycoprotein. It has a weight of approximately 300,000 Daltons. It cylindrical in appearance by electron microscopy approximately 16nm in length and 8nm in diameter. The main ion channel is composed of a water pore that runs through the entire length of the protein. If viewed from the synaptic cleft, the protein will look like a pseudo-symmetrical rosette shown in the picture below composed of 10 different alpha and 4 different beta subunits. | |||
*<scene name='58/584302/Cv/1'>Side view</scene>. | |||
*<scene name='58/584302/Cv/2'>View from extracellular side</scene>. | |||
*<scene name='58/584302/Cv/3'>View from cytoplasmic side</scene>. | |||
*[[Alpha-bungarotoxin]] is a nicotinic cholinergic antagonist that is found within the venom of ''Bungarus multicinctus'', a South-asian snake belonging to a group commonly known as kraits. | *[[Alpha-bungarotoxin]] is a nicotinic cholinergic antagonist that is found within the venom of ''Bungarus multicinctus'', a South-asian snake belonging to a group commonly known as kraits. | ||
*[[Binding site of AChR]] | *[[Binding site of AChR]] | ||
