Receptor: Difference between revisions

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*[[Molecular Playground/Glutamate Receptor|AMPA glutamate receptor]] by [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].

~~ull~~ view of the glutamate receptor shows the overall structure (amino-terminal, ligand-binding and transmembrane domains) in both <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_black_background/6'>ribbon</scene>(MF) and <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_spacefill/2'>spacefilling</scene> models.

Full view of the glutamate receptor shows the overall structure (amino-terminal, ligand-binding and transmembrane domains) in both <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_black_background/6'>ribbon</scene> (MF) and <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_spacefill/2'>spacefilling</scene> models.

Zooming in at the top of the receptor (<scene name='User:Mariel_Feliciano/sandbox_1/Amino_terminal_domains/2'>Amino Terminal Domains</scene>)(RCB) one can view the amino terminal domain, which is a part of the extracellular domain. This domain is implicated in receptor assembly, trafficking, and localization.

Zooming in at the top of the receptor (<scene name='User:Mariel_Feliciano/sandbox_1/Amino_terminal_domains/2'>Amino Terminal Domains</scene>) (RCB) one can view the amino terminal domain, which is a part of the extracellular domain. This domain is implicated in receptor assembly, trafficking, and localization.

Moving toward the bottom of the receptor (<scene name='Molecular_Playground/Glutamate_Receptor/Transmembrane_domains/5'>Transmembrane Domain</scene>) (SM) one can view the transmembrane domain. Here is the same domain separated from the rest of the protein.<scene name='Molecular_Playground/Glutamate_Receptor/Transmembrane_domains_pore2/1'>Transmembrane Domain</scene>.(DM) This domain widens in response to glutamate binding allowing for positive ions to pass through the post-synaptic membrane.

This view (<scene name='Molecular_Playground/Glutamate_Receptor/Glu_antagoinist/2'>receptor antagonist</scene>) highlights the area where a receptor antagonist, 2K200225, will bind.

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@@ Line 44: / Line 44: @@
 *[[Molecular Playground/Glutamate Receptor|AMPA glutamate receptor]] by [http://www.umass.edu/cbi/ University of Massachusetts Amherst Chemistry-Biology Interface Program] at UMass Amherst and on display at the [http://www.molecularplayground.org/ Molecular Playground].
-ull view of the glutamate receptor shows the overall structure (amino-terminal, ligand-binding and transmembrane domains) in both <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_black_background/6'>ribbon</scene>(MF) and <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_spacefill/2'>spacefilling</scene> models.
+Full view of the glutamate receptor shows the overall structure (amino-terminal, ligand-binding and transmembrane domains) in both <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_black_background/6'>ribbon</scene> (MF) and <scene name='User:Mariel_Feliciano/sandbox_1/Full_view_spacefill/2'>spacefilling</scene> models.
-Zooming in at the top of the receptor (<scene name='User:Mariel_Feliciano/sandbox_1/Amino_terminal_domains/2'>Amino Terminal Domains</scene>)(RCB) one can view the amino terminal domain, which is a part of the extracellular domain. This domain is implicated in receptor assembly, trafficking, and localization.
+Zooming in at the top of the receptor (<scene name='User:Mariel_Feliciano/sandbox_1/Amino_terminal_domains/2'>Amino Terminal Domains</scene>) (RCB) one can view the amino terminal domain, which is a part of the extracellular domain. This domain is implicated in receptor assembly, trafficking, and localization.
-Moving toward the bottom of the receptor (<scene name='Molecular_Playground/Glutamate_Receptor/Transmembrane_domains/5'>Transmembrane Domain</scene>) (SM) one can view the transmembrane domain.  Here is the same domain separated from the rest of the protein.<scene name='Molecular_Playground/Glutamate_Receptor/Transmembrane_domains_pore2/1'>Transmembrane Domain</scene>.(DM)  This domain widens in response to glutamate binding allowing for positive ions to pass through the post-synaptic membrane.
+Moving toward the bottom of the receptor (<scene name='Molecular_Playground/Glutamate_Receptor/Transmembrane_domains/5'>Transmembrane Domain</scene>) (SM) one can view the transmembrane domain. Here is the same domain separated from the rest of the protein.<scene name='Molecular_Playground/Glutamate_Receptor/Transmembrane_domains_pore2/1'>Transmembrane Domain</scene>.(DM)  This domain widens in response to glutamate binding allowing for positive ions to pass through the post-synaptic membrane.
 This view (<scene name='Molecular_Playground/Glutamate_Receptor/Glu_antagoinist/2'>receptor antagonist</scene>) highlights the area where a receptor antagonist, 2K200225, will bind.