1io8: Difference between revisions
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<StructureSection load='1io8' size='340' side='right'caption='[[1io8]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='1io8' size='340' side='right'caption='[[1io8]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1io8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1io8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IO8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IO8 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1io8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1io8 OCA], [https://pdbe.org/1io8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1io8 RCSB], [https://www.ebi.ac.uk/pdbsum/1io8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1io8 ProSAT], [https://www.topsan.org/Proteins/RSGI/1io8 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1io8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1io8 OCA], [https://pdbe.org/1io8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1io8 RCSB], [https://www.ebi.ac.uk/pdbsum/1io8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1io8 ProSAT], [https://www.topsan.org/Proteins/RSGI/1io8 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/CP119_SULAC CP119_SULAC] The endogenous substrate is not known. In vitro, catalyzes the H(2)O(2)-dependent epoxidation of styrene, cis-beta-methylstyrene, and cis-stilbene with retention of stereochemistry. Is able to use cumene hydroperoxide (CHP) or tert-butyl hydroperoxide (TBHP) instead of H(2)O(2) as the electron acceptor. Can also hydroxylate fatty acids such as lauric acid.<ref>PMID:10799487</ref> <ref>PMID:12010041</ref> <ref>PMID:18157853</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Saccharolobus solfataricus]] | ||
[[Category: | [[Category: Adachi S]] | ||
[[Category: | [[Category: Park S-Y]] | ||
[[Category: Shiro | [[Category: Shiro Y]] | ||
[[Category: Sligar | [[Category: Sligar SG]] | ||
[[Category: Yamane | [[Category: Yamane K]] | ||
Revision as of 23:34, 27 December 2023
Thermophilic cytochrome P450 (CYP119) from sulfolobus solfataricus: High resolution structural origin of its thermostability and functional properties
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