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==Solution structure of human ubiquitin conjugating enzyme Ube2g2==
==Solution structure of human ubiquitin conjugating enzyme Ube2g2==
<StructureSection load='2kly' size='340' side='right'caption='[[2kly]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2kly' size='340' side='right'caption='[[2kly]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2kly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLY FirstGlance]. <br>
<table><tr><td colspan='2'>[[2kly]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KLY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KLY FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">UBE2G2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ubiquitin--protein_ligase Ubiquitin--protein ligase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.19 6.3.2.19] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kly OCA], [https://pdbe.org/2kly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kly RCSB], [https://www.ebi.ac.uk/pdbsum/2kly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kly ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kly FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kly OCA], [https://pdbe.org/2kly PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kly RCSB], [https://www.ebi.ac.uk/pdbsum/2kly PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kly ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UB2G2_HUMAN UB2G2_HUMAN]] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).<ref>PMID:20061386</ref> <ref>PMID:22607976</ref>
[https://www.uniprot.org/uniprot/UB2G2_HUMAN UB2G2_HUMAN] Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination. Involved in endoplasmic reticulum-associated degradation (ERAD).<ref>PMID:20061386</ref> <ref>PMID:22607976</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ubiquitin--protein ligase]]
[[Category: Bocik W]]
[[Category: Bocik, W]]
[[Category: Ju T]]
[[Category: Ju, T]]
[[Category: Majumdar A]]
[[Category: Majumdar, A]]
[[Category: Tolman JR]]
[[Category: Tolman, J R]]
[[Category: Alpha beta fold]]
[[Category: Atp-binding]]
[[Category: Ligase]]
[[Category: Nucleotide-binding]]
[[Category: Ubl conjugation pathway]]
Retrieved from "https://proteopedia.org/2kly"