Sandbox Reserved 1670: Difference between revisions
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== Important amino acids== | == Important amino acids== | ||
NAD+ binding site has 19 catalytic residues which consist of Ile155–Asn159, Lys182, Gly219, Ile233–Ser236, Ala239, Leu242, Glu257, Leu258, Gly259, Cys291, Glu391, and Phe393 | NAD+ binding site has 19 catalytic residues which consist of Ile155–Asn159, Lys182, Gly219, Ile233–Ser236, Ala239, Leu242, Glu257, Leu258, Gly259, Cys291, Glu391, and Phe393 | ||
4 catalytic amino acids known as the | 4 catalytic amino acids known as the <scene name='87/873232/Catalytic_residues/4'>Catalytic Tetrad</scene> consisting of Asn159, Glu257, Gly288, and Cys291. Cys291 can be found to be mutated to an Ala <scene name='87/873232/Mutated_catalytic_tetrad/3'>Mutated Catalytic Tetrad</scene> | ||