Sandbox Reserved 1670: Difference between revisions
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4 catalytic amino acids known as the <scene name='87/873232/Catalytic_residues/4'>Catalytic Tetrad</scene> consisting of Asn159, Glu257, Gly288, and Cys291. Cys291 can be found to be mutated to an Ala <scene name='87/873232/Mutated_catalytic_tetrad/3'>Mutated Catalytic Tetrad</scene> | 4 catalytic amino acids known as the <scene name='87/873232/Catalytic_residues/4'>Catalytic Tetrad</scene> consisting of Asn159, Glu257, Gly288, and Cys291. Cys291 can be found to be mutated to an Ala <scene name='87/873232/Mutated_catalytic_tetrad/3'>Mutated Catalytic Tetrad</scene> | ||
The residues that were affected the most if mutated were mutations of Asn159, Trp160, Ser292, Leu419, and Phe456, this is because they are located closely to the protein active site. | |||
There are two ligands in each of the chains in the homodimer <scene name='87/873232/Ligands/2'>NAD and Octanal</scene> | There are two ligands in each of the chains in the homodimer <scene name='87/873232/Ligands/2'>NAD and Octanal</scene> | ||
