2m0r: Difference between revisions

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==Solution structure and dynamics of human S100A14==
==Solution structure and dynamics of human S100A14==
<StructureSection load='2m0r' size='340' side='right'caption='[[2m0r]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
<StructureSection load='2m0r' size='340' side='right'caption='[[2m0r]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2m0r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0R FirstGlance]. <br>
<table><tr><td colspan='2'>[[2m0r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0R FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">S100A14, S100A15 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0r OCA], [https://pdbe.org/2m0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0r RCSB], [https://www.ebi.ac.uk/pdbsum/2m0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0r ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0r OCA], [https://pdbe.org/2m0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0r RCSB], [https://www.ebi.ac.uk/pdbsum/2m0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0r ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/S10AE_HUMAN S10AE_HUMAN]] Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.<ref>PMID:21559403</ref> <ref>PMID:22032898</ref> <ref>PMID:22451655</ref>
[https://www.uniprot.org/uniprot/S10AE_HUMAN S10AE_HUMAN] Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.<ref>PMID:21559403</ref> <ref>PMID:22032898</ref> <ref>PMID:22451655</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bertini, I]]
[[Category: Bertini I]]
[[Category: Borsi, V]]
[[Category: Borsi V]]
[[Category: Cerofolini, L]]
[[Category: Cerofolini L]]
[[Category: Fragai, M]]
[[Category: Das Gupta S]]
[[Category: Gupta, S Das]]
[[Category: Fragai M]]
[[Category: Luchinat, C]]
[[Category: Luchinat C]]
[[Category: Ef-hand protein]]
[[Category: Metal binding protein]]
[[Category: Protein dynamic]]