2m0r: Difference between revisions
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==Solution structure and dynamics of human S100A14== | ==Solution structure and dynamics of human S100A14== | ||
<StructureSection load='2m0r' size='340' side='right'caption='[[2m0r | <StructureSection load='2m0r' size='340' side='right'caption='[[2m0r]]' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2m0r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[2m0r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2M0R FirstGlance]. <br> | ||
</td></tr> | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0r OCA], [https://pdbe.org/2m0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0r RCSB], [https://www.ebi.ac.uk/pdbsum/2m0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0r ProSAT]</span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2m0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2m0r OCA], [https://pdbe.org/2m0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2m0r RCSB], [https://www.ebi.ac.uk/pdbsum/2m0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2m0r ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/S10AE_HUMAN S10AE_HUMAN] Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.<ref>PMID:21559403</ref> <ref>PMID:22032898</ref> <ref>PMID:22451655</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bertini | [[Category: Bertini I]] | ||
[[Category: Borsi | [[Category: Borsi V]] | ||
[[Category: Cerofolini | [[Category: Cerofolini L]] | ||
[[Category: | [[Category: Das Gupta S]] | ||
[[Category: | [[Category: Fragai M]] | ||
[[Category: Luchinat | [[Category: Luchinat C]] | ||