5xwe: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5xwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ophiophagus_hannah Ophiophagus hannah]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XWE FirstGlance]. <br>
<table><tr><td colspan='2'>[[5xwe]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ophiophagus_hannah Ophiophagus hannah]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XWE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwe OCA], [https://pdbe.org/5xwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xwe RCSB], [https://www.ebi.ac.uk/pdbsum/5xwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwe ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xwe OCA], [https://pdbe.org/5xwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xwe RCSB], [https://www.ebi.ac.uk/pdbsum/5xwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xwe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/3S11H_OPHHA 3S11H_OPHHA]] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775]  
[https://www.uniprot.org/uniprot/3S11H_OPHHA 3S11H_OPHHA] Binds to muscle nicotinic acetylcholine receptor (nAChR) and inhibit acetylcholine from binding to the receptor, thereby impairing neuromuscular transmission.[UniProtKB:P60775]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Ophiophagus hannah]]
[[Category: Ophiophagus hannah]]
[[Category: Jobichen, C]]
[[Category: Jobichen C]]
[[Category: Kini, R M]]
[[Category: Kini RM]]
[[Category: Roy, A]]
[[Category: Roy A]]
[[Category: Sivaraman, J]]
[[Category: Sivaraman J]]
[[Category: Snake venom]]
[[Category: Three finger toxin]]
[[Category: Toxin]]

Latest revision as of 08:16, 22 November 2023

Structure of a three finger toxin from Ophiophagus hannah venom

5xwe, resolution 1.80Å

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