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==Structure determination of substrate binding domain of MecA==
==Structure determination of substrate binding domain of MecA==
<StructureSection load='2mk6' size='340' side='right'caption='[[2mk6]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2mk6' size='340' side='right'caption='[[2mk6]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mk6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._spizizenii_atcc_6633 Bacillus subtilis subsp. spizizenii atcc 6633]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MK6 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mk6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._spizizenii_ATCC_6633_=_JCM_2499 Bacillus subtilis subsp. spizizenii ATCC 6633 = JCM 2499]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MK6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MK6 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BSU6633_15767, mecA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=703612 Bacillus subtilis subsp. spizizenii ATCC 6633])</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk6 OCA], [https://pdbe.org/2mk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mk6 RCSB], [https://www.ebi.ac.uk/pdbsum/2mk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk6 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mk6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mk6 OCA], [https://pdbe.org/2mk6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mk6 RCSB], [https://www.ebi.ac.uk/pdbsum/2mk6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mk6 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/D5N397_BACPN D5N397_BACPN]] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.[HAMAP-Rule:MF_01124]  
[https://www.uniprot.org/uniprot/A0A0J9X1W8_BACSC A0A0J9X1W8_BACSC]  
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus subtilis subsp. spizizenii atcc 6633]]
[[Category: Bacillus subtilis subsp. spizizenii ATCC 6633 = JCM 2499]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Jin, C]]
[[Category: Jin C]]
[[Category: Shi, Y]]
[[Category: Shi Y]]
[[Category: Zhang, Y]]
[[Category: Zhang Y]]
[[Category: Zhang, Y H]]
[[Category: Zhang Y-H]]
[[Category: Competence]]
[[Category: Gene regulation]]
[[Category: Meca]]
[[Category: Proteolysis]]
Retrieved from "https://proteopedia.org/2mk6"