Isopeptide bond: Difference between revisions
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*Poly-ubiquitins<ref name="hiranyakorn">PMID: 32731397</ref>. | *Poly-ubiquitins<ref name="hiranyakorn">PMID: 32731397</ref>. | ||
*Intermolecular (between molecule) isopeptide bonds that link bacterial pilin monomers into long chains of pili are formed enzymatically by a cysteine transpeptidase "sortase"<ref name="kang2009">PMID: 19497855</ref>. However, the same pilins have multiple intramolecular (within molecule) isopeptide bonds that appear to form spontaneously<ref name="kang2009" />. | *Intermolecular (between molecule) isopeptide bonds that link bacterial pilin monomers into long chains of pili are formed enzymatically by a cysteine transpeptidase "sortase"<ref name="kang2009">PMID: 19497855</ref>. However, the same pilins have multiple intramolecular (within molecule) isopeptide bonds that appear to form spontaneously<ref name="kang2009" />. | ||
==Cleavage== | |||
Isopeptidases are enzymes that cleave isopeptide bonds. These include | |||
*Sentrin/SUMO-specific proteases (SENP) have isopeptidase activity that can deconjugate SUMO (small ubiquitin-like modifier) from its conjugates<ref>PMID: 33946350</ref>. | |||
==Frequency== | ==Frequency== | ||
