2nyt: Difference between revisions

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<StructureSection load='2nyt' size='340' side='right'caption='[[2nyt]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='2nyt' size='340' side='right'caption='[[2nyt]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2nyt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NYT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NYT FirstGlance]. <br>
<table><tr><td colspan='2'>[[2nyt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NYT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2NYT FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">APOBEC2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nyt OCA], [https://pdbe.org/2nyt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nyt RCSB], [https://www.ebi.ac.uk/pdbsum/2nyt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nyt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2nyt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2nyt OCA], [https://pdbe.org/2nyt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2nyt RCSB], [https://www.ebi.ac.uk/pdbsum/2nyt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2nyt ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ABEC2_HUMAN ABEC2_HUMAN]] Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.<ref>PMID:21496894</ref>
[https://www.uniprot.org/uniprot/ABEC2_HUMAN ABEC2_HUMAN] Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.<ref>PMID:21496894</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bransteitter, R]]
[[Category: Bransteitter R]]
[[Category: Chen, X]]
[[Category: Chen X]]
[[Category: Goodman, M]]
[[Category: Goodman M]]
[[Category: Klein, M]]
[[Category: Klein M]]
[[Category: Prochnow, C]]
[[Category: Prochnow C]]
[[Category: Apobec]]
[[Category: Cytidine deaminase]]
[[Category: Hydrolase]]
[[Category: Zinc-ion binding]]
Retrieved from "https://proteopedia.org/2nyt"