2ofp: Difference between revisions

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<StructureSection load='2ofp' size='340' side='right'caption='[[2ofp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='2ofp' size='340' side='right'caption='[[2ofp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2ofp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OFP FirstGlance]. <br>
<table><tr><td colspan='2'>[[2ofp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OFP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2OFP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PAF:PANTOATE'>PAF</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ks9|1ks9]], [[1yjq|1yjq]], [[1yon|1yon]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DIO:1,4-DIETHYLENE+DIOXIDE'>DIO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PAF:PANTOATE'>PAF</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">panE, apbA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/2-dehydropantoate_2-reductase 2-dehydropantoate 2-reductase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.169 1.1.1.169] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ofp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ofp OCA], [https://pdbe.org/2ofp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ofp RCSB], [https://www.ebi.ac.uk/pdbsum/2ofp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ofp ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ofp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ofp OCA], [https://pdbe.org/2ofp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ofp RCSB], [https://www.ebi.ac.uk/pdbsum/2ofp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ofp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PANE_ECOLI PANE_ECOLI]] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.  
[https://www.uniprot.org/uniprot/PANE_ECOLI PANE_ECOLI] Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: 2-dehydropantoate 2-reductase]]
[[Category: Escherichia coli K-12]]
[[Category: Ecoli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Abell, C]]
[[Category: Abell C]]
[[Category: Blundell, T L]]
[[Category: Blundell TL]]
[[Category: Chirgadze, D Y]]
[[Category: Chirgadze DY]]
[[Category: Ciulli, A]]
[[Category: Ciulli A]]
[[Category: Smith, A G]]
[[Category: Smith AG]]
[[Category: Apba]]
[[Category: Ketopantoate reductase]]
[[Category: Oxidoreductase]]
[[Category: Pane]]
[[Category: Ternary complex]]
Retrieved from "https://proteopedia.org/2ofp"