2pso: Difference between revisions

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<StructureSection load='2pso' size='340' side='right'caption='[[2pso]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='2pso' size='340' side='right'caption='[[2pso]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2pso]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PSO FirstGlance]. <br>
<table><tr><td colspan='2'>[[2pso]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2PSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2PSO FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">STARD13, DLC2, GT650 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pso OCA], [https://pdbe.org/2pso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pso RCSB], [https://www.ebi.ac.uk/pdbsum/2pso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pso ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2pso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2pso OCA], [https://pdbe.org/2pso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2pso RCSB], [https://www.ebi.ac.uk/pdbsum/2pso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2pso ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/STA13_HUMAN STA13_HUMAN]] GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.<ref>PMID:14697242</ref> <ref>PMID:16217026</ref>
[https://www.uniprot.org/uniprot/STA13_HUMAN STA13_HUMAN] GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells.<ref>PMID:14697242</ref> <ref>PMID:16217026</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Berg, S Van den]]
[[Category: Berglund H]]
[[Category: Berglund, H]]
[[Category: Busam R]]
[[Category: Busam, R]]
[[Category: Collins R]]
[[Category: Collins, R]]
[[Category: Dahlgren LG]]
[[Category: Dahlgren, L G]]
[[Category: Edwards A]]
[[Category: Edwards, A]]
[[Category: Flodin S]]
[[Category: Flodin, S]]
[[Category: Flores A]]
[[Category: Flores, A]]
[[Category: Graslund S]]
[[Category: Graslund, S]]
[[Category: Hallberg BM]]
[[Category: Hallberg, B M]]
[[Category: Hammarstrom M]]
[[Category: Hammarstrom, M]]
[[Category: Holmberg-Schiavone L]]
[[Category: Holmberg-Schiavone, L]]
[[Category: Johansson I]]
[[Category: Johansson, I]]
[[Category: Kallas A]]
[[Category: Kallas, A]]
[[Category: Karlberg T]]
[[Category: Karlberg, T]]
[[Category: Kotenyova T]]
[[Category: Kotenyova, T]]
[[Category: Lehtio L]]
[[Category: Lehtio, L]]
[[Category: Moche M]]
[[Category: Moche, M]]
[[Category: Nordlund P]]
[[Category: Nordlund, P]]
[[Category: Nyman T]]
[[Category: Nyman, T]]
[[Category: Ogg D]]
[[Category: Ogg, D]]
[[Category: Persson C]]
[[Category: Persson, C]]
[[Category: Sagemark J]]
[[Category: Structural genomic]]
[[Category: Stenmark P]]
[[Category: Sagemark, J]]
[[Category: Sundstrom M]]
[[Category: Stenmark, P]]
[[Category: Thorsell AG]]
[[Category: Sundstrom, M]]
[[Category: Van den Berg S]]
[[Category: Thorsell, A G]]
[[Category: Weigelt J]]
[[Category: Weigelt, J]]
[[Category: Welin M]]
[[Category: Welin, M]]
[[Category: Alpha and beta protein]]
[[Category: Helix swapping]]
[[Category: Lipid binding]]
[[Category: Sgc]]
[[Category: Unknown function]]