1esc: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,329,897 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,329,897 edits
No edit summary
Line 1: Line 1:
[[Image:1esc.gif|left|200px]]
{{Seed}}
[[Image:1esc.png|left|200px]]


<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1esc|  PDB=1esc  |  SCENE=  }}  
{{STRUCTURE_1esc|  PDB=1esc  |  SCENE=  }}  


'''THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES'''
===THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES===




==Overview==
<!--
The crystal structure of a novel esterase from Streptomyces scabies, a causal agent of the potato scab disease, was solved at 2.1 A resolution. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases. The active site contains a dyad of Ser 14 and His 283, closely resembling two of the three components of typical Ser-His-Asp(Glu) triads from other serine hydrolases. Proper orientation of the active site imidazol is maintained by a hydrogen bond between the N delta-H group and a main chain oxygen. Thus, the enzyme constitutes the first known natural variation of the chymotrypsin-like triad in which a carboxylic acid is replaced by a neutral hydrogen-bond acceptor.
The line below this paragraph, {{ABSTRACT_PUBMED_7773790}}, adds the Publication Abstract to the page
(as it appears on PubMed at http://www.pubmed.gov), where 7773790 is the PubMed ID number.
-->
{{ABSTRACT_PUBMED_7773790}}


==About this Structure==
==About this Structure==
Line 28: Line 32:
[[Category: Swenson, L.]]
[[Category: Swenson, L.]]
[[Category: Wei, Y.]]
[[Category: Wei, Y.]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 15:27:53 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:48:24 2008''

Revision as of 22:48, 30 June 2008

File:1esc.png

Template:STRUCTURE 1esc

THE MOLECULAR MECHANISM OF ENANTIORECOGNITION BY ESTERASES

Template:ABSTRACT PUBMED 7773790

About this Structure

1ESC is a Single protein structure of sequence from Streptomyces scabiei. Full crystallographic information is available from OCA.

Reference

A novel variant of the catalytic triad in the Streptomyces scabies esterase., Wei Y, Schottel JL, Derewenda U, Swenson L, Patkar S, Derewenda ZS, Nat Struct Biol. 1995 Mar;2(3):218-23. PMID:7773790

Page seeded by OCA on Tue Jul 1 01:48:24 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=1esc&oldid=593833"