Isopeptide bond: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) |
Eric Martz (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
<Structure load='' size='350' frame='true' align='right' caption='' scene='56/560856/Isopeptide_bond/4' /> | <Structure load='' size='350' frame='true' align='right' caption='' scene='56/560856/Isopeptide_bond/4' /> | ||
An ''isopeptide bond'' is an [https://en.wikipedia.org/wiki/Amide amide bond] between the sidechain of one [[amino acid]] and the sidechain or main chain terminus of another amino acid, or a ligand. Isopeptide bonds are sometimes called [https://en.wikipedia.org/wiki/Lactam lactams]<ref name="lactam">PMID: 24446383</ref>. | An ''isopeptide bond'' is an [https://en.wikipedia.org/wiki/Amide amide bond] between the sidechain of one [[amino acid]] and the sidechain or main chain terminus of another amino acid, or a ligand. Isopeptide bonds are sometimes called [https://en.wikipedia.org/wiki/Lactam lactams]<ref name="lactam">PMID: 24446383</ref><ref name="5vbl">PMID: 28528775</ref>.<br>[[Image:Isopeptide-bond.jpg|300px]] | ||
<br>[[Image:Isopeptide-bond.jpg|300px]] | |||
Isopeptide bonds often form covalent links between polypeptide backbones. This is in contrast to the much more common [[Peptide bond|peptide (''eupeptide'') bonds]] between amino acid main chain atoms that form the polypeptide backbones of proteins. Isopepide bonds are rare (as are [[lysine-cysteine NOS bonds]]). [[Disulfide bonds]] are a much more common form of covalent linkage between polypeptide chains. | Isopeptide bonds often form covalent links between polypeptide backbones. This is in contrast to the much more common [[Peptide bond|peptide (''eupeptide'') bonds]] between amino acid main chain atoms that form the polypeptide backbones of proteins. Isopepide bonds are rare (as are [[lysine-cysteine NOS bonds]]). [[Disulfide bonds]] are a much more common form of covalent linkage between polypeptide chains. | ||
