6wym: Difference between revisions

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<StructureSection load='6wym' size='340' side='right'caption='[[6wym]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6wym' size='340' side='right'caption='[[6wym]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6wym]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Myctu Myctu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WYM FirstGlance]. <br>
<table><tr><td colspan='2'>[[6wym]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6WYM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6WYM FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv0045c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83332 MYCTU])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wym OCA], [https://pdbe.org/6wym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wym RCSB], [https://www.ebi.ac.uk/pdbsum/6wym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wym ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6wym FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6wym OCA], [https://pdbe.org/6wym PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6wym RCSB], [https://www.ebi.ac.uk/pdbsum/6wym PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6wym ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/EST45_MYCTU EST45_MYCTU]] Esterase likely involved in ester/lipid metabolism. Shows strong substrate selectivity toward short, straight chain alkyl esters with the highest activity toward four atom chains. The physiological substrate is unknown (PubMed:25354081). Is able to hydrolyze ester bonds within a wide range of p-nitrophenyl derivatives (C2-C14) in vitro (PubMed:20957207).<ref>PMID:20957207</ref> <ref>PMID:25354081</ref>
[https://www.uniprot.org/uniprot/EST45_MYCTU EST45_MYCTU] Esterase likely involved in ester/lipid metabolism. Shows strong substrate selectivity toward short, straight chain alkyl esters with the highest activity toward four atom chains. The physiological substrate is unknown (PubMed:25354081). Is able to hydrolyze ester bonds within a wide range of p-nitrophenyl derivatives (C2-C14) in vitro (PubMed:20957207).<ref>PMID:20957207</ref> <ref>PMID:25354081</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Myctu]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Hoops, G C]]
[[Category: Hoops GC]]
[[Category: Johnson, R J]]
[[Category: Johnson RJ]]
[[Category: Macbeth, M R]]
[[Category: Macbeth MR]]
[[Category: Allosteric regulation]]
[[Category: Conformational change]]
[[Category: Hydrolase]]
[[Category: Serine esterase]]
Retrieved from "https://proteopedia.org/6wym"