6hvk: Difference between revisions

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==Pepducin UT-Pep2 a biased allosteric agonist of Urotensin-II receptor==
==Pepducin UT-Pep2 a biased allosteric agonist of Urotensin-II receptor==
<StructureSection load='6hvk' size='340' side='right'caption='[[6hvk]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='6hvk' size='340' side='right'caption='[[6hvk]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6hvk]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6q8l 6q8l]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HVK FirstGlance]. <br>
<table><tr><td colspan='2'>[[6hvk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=6q8l 6q8l]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6HVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6HVK FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hvk OCA], [https://pdbe.org/6hvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hvk RCSB], [https://www.ebi.ac.uk/pdbsum/6hvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hvk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6hvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6hvk OCA], [https://pdbe.org/6hvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6hvk RCSB], [https://www.ebi.ac.uk/pdbsum/6hvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6hvk ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/UR2R_HUMAN UR2R_HUMAN]] High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.<ref>PMID:14550283</ref>
[https://www.uniprot.org/uniprot/UR2R_HUMAN UR2R_HUMAN] High affinity receptor for urotensin-2 and urotensin-2B. The activity of this receptor is mediated by a G-protein that activate a phosphatidylinositol-calcium second messenger system.<ref>PMID:14550283</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Billard, E]]
[[Category: Billard E]]
[[Category: Carotenuto, A]]
[[Category: Carotenuto A]]
[[Category: Chatenet, D]]
[[Category: Chatenet D]]
[[Category: Fournier, A]]
[[Category: Fournier A]]
[[Category: Hebert, T E]]
[[Category: Hebert TE]]
[[Category: Hoang, T A]]
[[Category: Hoang TA]]
[[Category: Martin, R D]]
[[Category: Martin RD]]
[[Category: Myriam, L]]
[[Category: Myriam L]]
[[Category: Nassour, H]]
[[Category: Nassour H]]
[[Category: Novellino, E]]
[[Category: Novellino E]]
[[Category: Tanny, J C]]
[[Category: Tanny JC]]
[[Category: Allosteric modulator]]
[[Category: Cellular signaling]]
[[Category: G protein-coupled receptor]]
[[Category: Lipidated peptide]]
[[Category: Pepducin]]
[[Category: Peptide binding protein]]
[[Category: Urotensin ii receptor]]