7kq3: Difference between revisions

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<StructureSection load='7kq3' size='340' side='right'caption='[[7kq3]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
<StructureSection load='7kq3' size='340' side='right'caption='[[7kq3]], [[Resolution|resolution]] 2.69&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[7kq3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bilw3 Bilw3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KQ3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[7kq3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bilophila_wadsworthia_3_1_6 Bilophila wadsworthia 3_1_6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7KQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7KQ3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8X3:2-hydroxyethylsulfonic+acid'>8X3</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.688&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">islA, iseG, HMPREF0179_00639 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=563192 BILW3])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8X3:2-hydroxyethylsulfonic+acid'>8X3</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kq3 OCA], [https://pdbe.org/7kq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kq3 RCSB], [https://www.ebi.ac.uk/pdbsum/7kq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kq3 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7kq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7kq3 OCA], [https://pdbe.org/7kq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7kq3 RCSB], [https://www.ebi.ac.uk/pdbsum/7kq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7kq3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/ISLA_BILW3 ISLA_BILW3]] Involved in an anaerobic respiration pathway that converts the sulfonate taurine (2-aminoethanesulfonate) to ammonia, acetate and sulfide. Catalyzes the radical-mediated C-S bond cleavage of isethionate (2-hydroxyethanesulfonate) to form sulfite and acetaldehyde. Is not able to use any alternate organosulfonate or (S)-1,2-propanediol or choline as a substrate, showing that this enzyme is highly specific for isethionate.<ref>PMID:30718429</ref>
[https://www.uniprot.org/uniprot/ISLA_BILW3 ISLA_BILW3] Involved in an anaerobic respiration pathway that converts the sulfonate taurine (2-aminoethanesulfonate) to ammonia, acetate and sulfide. Catalyzes the radical-mediated C-S bond cleavage of isethionate (2-hydroxyethanesulfonate) to form sulfite and acetaldehyde. Is not able to use any alternate organosulfonate or (S)-1,2-propanediol or choline as a substrate, showing that this enzyme is highly specific for isethionate.<ref>PMID:30718429</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bilw3]]
[[Category: Bilophila wadsworthia 3_1_6]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Backman, L R.F]]
[[Category: Backman LRF]]
[[Category: Dawson, C D]]
[[Category: Dawson CD]]
[[Category: Drennan, C L]]
[[Category: Drennan CL]]
[[Category: Carbon-sulfur bond cleavage]]
[[Category: Glycyl radical enzyme]]
[[Category: Isethionate-sulfite lyase]]
[[Category: Lyase]]
[[Category: Microbiome]]
Retrieved from "https://proteopedia.org/7kq3"