1vya: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
<StructureSection load='1vya' size='340' side='right'caption='[[1vya]], [[Resolution|resolution]] 2.05Å' scene=''> | <StructureSection load='1vya' size='340' side='right'caption='[[1vya]], [[Resolution|resolution]] 2.05Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1vya]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/ | <table><tr><td colspan='2'>[[1vya]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Zea_mays Zea mays]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VYA FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vya OCA], [https://pdbe.org/1vya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vya RCSB], [https://www.ebi.ac.uk/pdbsum/1vya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vya ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vya OCA], [https://pdbe.org/1vya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vya RCSB], [https://www.ebi.ac.uk/pdbsum/1vya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vya ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/NDK1_MAIZE NDK1_MAIZE] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity). Involved in transcription regulation (Probable). Has G-quadruplex (G4) DNA-binding activity, which is independent of its nucleotide-binding and kinase activity. Binds folded G4 with low nanomolar affinity and corresponding unfolded G-rich DNA more weakly. Stabilizes folded G4s regardless of whether they are prefolded or not (PubMed:25679041).[UniProtKB:P36010]<ref>PMID:25679041</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 24: | Line 26: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Zea mays]] | ||
[[Category: Kopylov M]] | |||
[[Category: Kopylov | [[Category: Stroupe ME]] | ||
[[Category: Stroupe | |||
