1wpd: Difference between revisions

<StructureSection load='1wpd' size='340' side='right'caption='[[1wpd]]' scene=''>

<table><tr><td colspan='2'>[[1wpd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Heterometrus_spinifer Heterometrus spinifer] and [https://en.wikipedia.org/wiki/Scorpio_palmatus Scorpio palmatus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WPD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WPD FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wpd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wpd OCA], [https://pdbe.org/1wpd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wpd RCSB], [https://www.ebi.ac.uk/pdbsum/1wpd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wpd ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/KAX62_SCOPA KAX62_SCOPA] Blocks voltage-gated potassium channels Kv1.2/KCNA2 (IC(50)=0.12-0.8 nM), KCa3.1/KCNN4 (IC(50)=1-2.2 nM), Shaker B (IC(50)=2.39-80 nM), Kv1.1/KCNA1 (IC(50)=37-45 or no activity, depending on the study), Kv1.3/KCNA3 (IC(50)=150-180 or no activity, depending on the study).<ref>PMID:10888198</ref> <ref>PMID:10920011</ref> <ref>PMID:12527813</ref> <ref>PMID:15498765</ref> <ref>PMID:18042681</ref> <ref>PMID:9022673</ref> <ref>PMID:9136903</ref>  

[[Category: Andreotti N]]

[[Category: Beeton C]]

[[Category: Chandy GK]]

[[Category: Darbon H]]

[[Category: De Waard M]]

[[Category: Ferrat G]]

[[Category: Regaya I]]

[[Category: Sabatier JM]]