Sandbox Reserved 1684: Difference between revisions
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< | <StructureSection load='1rdr' size='340' side='right' caption='Polio RDRP''> | ||
==Poliovirus RNA-Dependent RNA Polymerase== | ==Poliovirus RNA-Dependent RNA Polymerase== | ||
RNA-dependent RNA polymerases(RdRp)are one ofthe most versatile enzymes of RNA viruses that are vital for genome replication as well as for carrying out transcription. They have such a name due to their function where they use RNA template to synthesize mRNA which will later be translated into proteins and spread virus among the host. The core structural features of these polymerases are conserved, however, there is some divergence among their sequences. The structure of the RNA-dependent RNA polymerases resembles a cupped right hand which also consists of fingers, palm and thumb subdomains. In most cases catalysis involves several conserved aspartate residues together with <scene name='89/891374/Divalent_metal_ions/4'>divalent metal ions.</scene> | RNA-dependent RNA polymerases(RdRp)are one ofthe most versatile enzymes of RNA viruses that are vital for genome replication as well as for carrying out transcription. They have such a name due to their function where they use RNA template to synthesize mRNA which will later be translated into proteins and spread virus among the host. The core structural features of these polymerases are conserved, however, there is some divergence among their sequences. The structure of the RNA-dependent RNA polymerases resembles a cupped right hand which also consists of fingers, palm and thumb subdomains. In most cases catalysis involves several conserved aspartate residues together with <scene name='89/891374/Divalent_metal_ions/4'>divalent metal ions.</scene> | ||