7rx1: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1== | ==Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1== | ||
<StructureSection load='7rx1' size='340' side='right'caption='[[7rx1]]' scene=''> | <StructureSection load='7rx1' size='340' side='right'caption='[[7rx1]], [[Resolution|resolution]] 1.89Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RX1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7rx1]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vitis_rotundifolia Vitis rotundifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7RX1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7RX1 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rx1 OCA], [https://pdbe.org/7rx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rx1 RCSB], [https://www.ebi.ac.uk/pdbsum/7rx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rx1 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7rx1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7rx1 OCA], [https://pdbe.org/7rx1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7rx1 RCSB], [https://www.ebi.ac.uk/pdbsum/7rx1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7rx1 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/RUN1_VITRO RUN1_VITRO] Disease resistance (R) protein that confers resistance to multiple powdery and downy mildew by promoting cell death (PubMed:24033846, PubMed:31439792). Acts as a NAD(+) hydrolase (NADase): in response to activation, catalyzes cleavage of NAD(+) into ADP-D-ribose (ADPR) and nicotinamide; NAD(+) cleavage triggering a defense system that promotes cell death (PubMed:31439792). Also able to hydrolyze NADP(+), but not other NAD(+)-related molecules (PubMed:31439792).<ref>PMID:24033846</ref> <ref>PMID:31439792</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Vitis rotundifolia]] | |||
[[Category: Burdett H]] | [[Category: Burdett H]] | ||
[[Category: Kobe B]] | [[Category: Kobe B]] | ||
Latest revision as of 16:40, 18 October 2023
Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1
| ||||||||||||
