1vey: Difference between revisions

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<StructureSection load='1vey' size='340' side='right'caption='[[1vey]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
<StructureSection load='1vey' size='340' side='right'caption='[[1vey]], [[Resolution|resolution]] 3.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1vey]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"leptospira_icteroides"_noguchi_1919 "leptospira icteroides" noguchi 1919]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VEY FirstGlance]. <br>
<table><tr><td colspan='2'>[[1vey]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Leptospira_interrogans Leptospira interrogans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VEY FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.3&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sv2|1sv2]], [[1rn5|1rn5]], [[1vev|1vev]], [[1vez|1vez]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptide_deformylase Peptide deformylase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.88 3.5.1.88] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vey OCA], [https://pdbe.org/1vey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vey RCSB], [https://www.ebi.ac.uk/pdbsum/1vey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vey ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vey FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vey OCA], [https://pdbe.org/1vey PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vey RCSB], [https://www.ebi.ac.uk/pdbsum/1vey PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vey ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/DEF_LEPIN DEF_LEPIN]] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]  
[https://www.uniprot.org/uniprot/DEF_LEPIN DEF_LEPIN] Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity).[HAMAP-Rule:MF_00163]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Leptospira icteroides noguchi 1919]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Peptide deformylase]]
[[Category: Leptospira interrogans]]
[[Category: Gong, W]]
[[Category: Gong W]]
[[Category: Li, Y]]
[[Category: Li Y]]
[[Category: Song, X]]
[[Category: Song X]]
[[Category: Zhou, Z]]
[[Category: Zhou Z]]
[[Category: Closed conformation]]
[[Category: Hepe]]
[[Category: Hydrolase]]