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[[Image:1ffk.jpg|left|200px]]
[[Image:1ffk.png|left|200px]]


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==Overview==
{{ABSTRACT_10937989}}
The large ribosomal subunit catalyzes peptide bond formation and binds initiation, termination, and elongation factors. We have determined the crystal structure of the large ribosomal subunit from Haloarcula marismortui at 2.4 angstrom resolution, and it includes 2833 of the subunit's 3045 nucleotides and 27 of its 31 proteins. The domains of its RNAs all have irregular shapes and fit together in the ribosome like the pieces of a three-dimensional jigsaw puzzle to form a large, monolithic structure. Proteins are abundant everywhere on its surface except in the active site where peptide bond formation occurs and where it contacts the small subunit. Most of the proteins stabilize the structure by interacting with several RNA domains, often using idiosyncratically folded extensions that reach into the subunit's interior.


==About this Structure==
==About this Structure==
1FFK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. The following page contains interesting information on the relation of 1FFK with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb10_1.html Ribosome]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFK OCA].  
1FFK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Haloarcula_marismortui Haloarcula marismortui]. The following page contains interesting information on the relation of 1FFK with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb10_1.html Ribosome]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFK OCA].  
==Reference==
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution., Ban N, Nissen P, Hansen J, Moore PB, Steitz TA, Science. 2000 Aug 11;289(5481):905-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10937989 10937989]
[[Category: Haloarcula marismortui]]
[[Category: Haloarcula marismortui]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: Ribosome assembly]]
[[Category: Ribosome assembly]]
[[Category: Rna-rna]]
[[Category: Rna-rna]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 16:15:55 2008''
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 17:18:02 2008''

Revision as of 14:18, 26 June 2008

File:1ffk.png

Template:STRUCTURE 1ffk

CRYSTAL STRUCTURE OF THE LARGE RIBOSOMAL SUBUNIT FROM HALOARCULA MARISMORTUI AT 2.4 ANGSTROM RESOLUTION


Template:ABSTRACT 10937989

About this Structure

1FFK is a Protein complex structure of sequences from Haloarcula marismortui. The following page contains interesting information on the relation of 1FFK with [Ribosome]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 17:18:02 2008

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