2a63: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
Line 1: Line 1:


==Solution structure of a stably monomeric mutant of lambda Cro produced by substitutions in the ball-and-socket interface==
==Solution structure of a stably monomeric mutant of lambda Cro produced by substitutions in the ball-and-socket interface==
<StructureSection load='2a63' size='340' side='right'caption='[[2a63]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2a63' size='340' side='right'caption='[[2a63]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2a63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteriophage_lambda Bacteriophage lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A63 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2a63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A63 FirstGlance]. <br>
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">cro ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10710 Bacteriophage lambda])</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a63 OCA], [https://pdbe.org/2a63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a63 RCSB], [https://www.ebi.ac.uk/pdbsum/2a63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a63 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a63 OCA], [https://pdbe.org/2a63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a63 RCSB], [https://www.ebi.ac.uk/pdbsum/2a63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a63 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD]] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.  
[https://www.uniprot.org/uniprot/RCRO_LAMBD RCRO_LAMBD] Cro represses genes normally expressed in early phage development and is necessary for the late stage of lytic growth. It does this by binding to the OL and OR operators regions normally used by the repressor protein for lysogenic maintenance.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 32: Line 32:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacteriophage lambda]]
[[Category: Escherichia virus Lambda]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Atkinson, K R]]
[[Category: Atkinson KR]]
[[Category: Cordes, M H]]
[[Category: Cordes MH]]
[[Category: Dorn, L O.Van]]
[[Category: Newlove T]]
[[Category: Newlove, T]]
[[Category: Van Dorn LO]]
[[Category: Ball-and-socket]]
[[Category: Helix-turn-helix]]
[[Category: Monomer]]
[[Category: Viral protein]]
Retrieved from "https://proteopedia.org/2a63"