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==The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica==
==The Solution Structure of the Monomeric Copper, Zinc Superoxide Dismutase from Salmonella enterica==
<StructureSection load='2k4w' size='340' side='right'caption='[[2k4w]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
<StructureSection load='2k4w' size='340' side='right'caption='[[2k4w]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2k4w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_choleraesuis_choleraesuis Salmonella choleraesuis choleraesuis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K4W FirstGlance]. <br>
<table><tr><td colspan='2'>[[2k4w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Choleraesuis Salmonella enterica subsp. enterica serovar Choleraesuis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K4W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 30 models</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">sodC2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=119912 Salmonella choleraesuis choleraesuis])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CU1:COPPER+(I)+ION'>CU1</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k4w OCA], [https://pdbe.org/2k4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k4w RCSB], [https://www.ebi.ac.uk/pdbsum/2k4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k4w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k4w OCA], [https://pdbe.org/2k4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k4w RCSB], [https://www.ebi.ac.uk/pdbsum/2k4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k4w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[[https://www.uniprot.org/uniprot/Q704S6_SALET Q704S6_SALET]] Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).[RuleBase:RU000393]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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   <jmolCheckbox>
   <jmolCheckbox>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/2k4w_consurf.spt"</scriptWhenChecked>
     <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/2k4w_consurf.spt"</scriptWhenChecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
     <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
     <text>to colour the structure by Evolutionary Conservation</text>
     <text>to colour the structure by Evolutionary Conservation</text>
   </jmolCheckbox>
   </jmolCheckbox>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Salmonella choleraesuis choleraesuis]]
[[Category: Salmonella enterica subsp. enterica serovar Choleraesuis]]
[[Category: Superoxide dismutase]]
[[Category: Battistoni A]]
[[Category: Battistoni, A]]
[[Category: Jimenez B]]
[[Category: Jimenez, B]]
[[Category: Mori M]]
[[Category: Mori, M]]
[[Category: Piccioli M]]
[[Category: Piccioli, M]]
[[Category: Sette M]]
[[Category: SPINE, Structural Proteomics in Europe]]
[[Category: Sette, M]]
[[Category: Bioinorganic chemistry]]
[[Category: Copper]]
[[Category: Metal-binding]]
[[Category: Metalloenzyme]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nppsfa]]
[[Category: Oxidoreductase]]
[[Category: Solution structure]]
[[Category: Spine]]
[[Category: Structural genomic]]
[[Category: Structural proteomics in europe]]
[[Category: Zinc]]
Retrieved from "https://proteopedia.org/2k4w"