3e3j: Difference between revisions

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<StructureSection load='3e3j' size='340' side='right'caption='[[3e3j]], [[Resolution|resolution]] 6.70&Aring;' scene=''>
<StructureSection load='3e3j' size='340' side='right'caption='[[3e3j]], [[Resolution|resolution]] 6.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3e3j]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt7 Bpt7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E3J FirstGlance]. <br>
<table><tr><td colspan='2'>[[3e3j]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_T7 Escherichia phage T7] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3E3J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3E3J FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3e2e|3e2e]]</div></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 6.7&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10760 BPT7])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA-directed_RNA_polymerase DNA-directed RNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.6 2.7.7.6] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e3j OCA], [https://pdbe.org/3e3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e3j RCSB], [https://www.ebi.ac.uk/pdbsum/3e3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e3j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3e3j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3e3j OCA], [https://pdbe.org/3e3j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3e3j RCSB], [https://www.ebi.ac.uk/pdbsum/3e3j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3e3j ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/RPOL_BPT7 RPOL_BPT7]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of the late genes of T7. It is rifampicin-resistant. It recognizes a specific promoter sequence, unwinds the double-stranded RNA to expose the coding strand for templating, initiates transcription preferentially with a purine.  
[https://www.uniprot.org/uniprot/RPOL_BPT7 RPOL_BPT7] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Responsible for the transcription of the late genes of T7. It is rifampicin-resistant. It recognizes a specific promoter sequence, unwinds the double-stranded RNA to expose the coding strand for templating, initiates transcription preferentially with a purine.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bpt7]]
[[Category: Escherichia phage T7]]
[[Category: DNA-directed RNA polymerase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Bailey, S]]
[[Category: Synthetic construct]]
[[Category: Durniak, K J]]
[[Category: Bailey S]]
[[Category: Steitz, T A]]
[[Category: Durniak KJ]]
[[Category: Dna-directed rna polymerase]]
[[Category: Steitz TA]]
[[Category: Nucleotidyltransferase]]
[[Category: T7 rna polymerase]]
[[Category: Transcription]]
[[Category: Transferase]]
[[Category: Transferase-rna-dna complex]]