3g0y: Difference between revisions

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<StructureSection load='3g0y' size='340' side='right'caption='[[3g0y]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='3g0y' size='340' side='right'caption='[[3g0y]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3g0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G0Y FirstGlance]. <br>
<table><tr><td colspan='2'>[[3g0y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G0Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G0Y FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9A:3-({3-[(1S,4AS,6S,7S,9S,9AR)-1,6-DIMETHYL-2-OXODECAHYDRO-6,9-EPOXY-4A,7-METHANOBENZO[7]ANNULEN-1-YL]PROPANOYL}AMINO)-2,4-DIHYDROXYBENZOIC+ACID'>P9A</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gfx|2gfx]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P9A:3-({3-[(1S,4AS,6S,7S,9S,9AR)-1,6-DIMETHYL-2-OXODECAHYDRO-6,9-EPOXY-4A,7-METHANOBENZO[7]ANNULEN-1-YL]PROPANOYL}AMINO)-2,4-DIHYDROXYBENZOIC+ACID'>P9A</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">b1095, fabF, fabJ, JW1081 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-ketoacyl-[acyl-carrier-protein]_synthase_II Beta-ketoacyl-[acyl-carrier-protein] synthase II], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.179 2.3.1.179] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g0y OCA], [https://pdbe.org/3g0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g0y RCSB], [https://www.ebi.ac.uk/pdbsum/3g0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g0y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g0y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g0y OCA], [https://pdbe.org/3g0y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g0y RCSB], [https://www.ebi.ac.uk/pdbsum/3g0y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g0y ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/FABF_ECOLI FABF_ECOLI]] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis.  
[https://www.uniprot.org/uniprot/FABF_ECOLI FABF_ECOLI] Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthesis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ecoli]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Parthasarathy, G]]
[[Category: Parthasarathy G]]
[[Category: Soisson, S M]]
[[Category: Soisson SM]]
[[Category: Acyltransferase]]
[[Category: Antibiotic]]
[[Category: Fatty acid biosynthesis]]
[[Category: Ketoacyl synthase]]
[[Category: Lipid synthesis]]
[[Category: Transferase]]

Latest revision as of 06:55, 6 September 2023

Structure of E. coli FabF(C163Q) in complex with dihydroplatensimycin

3g0y, resolution 2.60Å

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