Clashes: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Eric Martz (talk | contribs) No edit summary |
Eric Martz (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
''Clashes'' in protein models, also called ''steric clashes'', occur when two non-bonded atoms are impossibly close to each other. This happens when the [[van der Waals radii]] of the atoms overlap; that is, when two atoms are occupying the same space. Clashes typically occur in lower [[resolution]] models due to the difficulties of obeying all chemical constraints while optimizing the fit of the model to the experimental data. Clashes are more common in X-ray crystallographic models with resolutions of 3.0 Å or worse, or in cryo-EM models. (NMR models generally lack clashes because they are forced to obey chemical constraints.) | ''Clashes'' in protein models, also called ''steric clashes'', occur when two non-bonded atoms are impossibly close to each other. This happens when the [[van der Waals radii]] of the atoms overlap; that is, when two atoms are occupying the same space. Clashes typically occur in lower [[resolution]] models due to the difficulties of obeying all chemical constraints while optimizing the fit of the model to the experimental data. Clashes are more common in [[X-ray crystallography|X-ray crystallographic]] models with resolutions of 3.0 Å or worse, or in [[cryo-EM]] models. ([[NMR]] models generally lack clashes because they are forced to obey chemical constraints.) | ||
==Clashes Dictate Protein Secondary Structure== | ==Clashes Dictate Protein Secondary Structure== | ||
